Last edited by Malakinos
Thursday, April 30, 2020 | History

6 edition of The etiology of human breast cancer found in the catalog.

The etiology of human breast cancer

endocrine, genetic, viral, immunologic and other considerations

by Anaxagoras N. Papaioannou

  • 67 Want to read
  • 38 Currently reading

Published by Springer-Verlag in Berlin, New York .
Written in English

    Subjects:
  • Breast -- Cancer -- Endocrine aspects.,
  • Breast -- Cancer -- Genetic aspects.,
  • Breast -- Cancer -- Immunological aspects.,
  • Viral carcinogenesis.

  • Edition Notes

    Includes bibliographies.

    Statement[by] A. N. Papaioannou.
    Classifications
    LC ClassificationsRC280.B8 P27
    The Physical Object
    Paginationxii, 216 p.
    Number of Pages216
    ID Numbers
    Open LibraryOL5043003M
    ISBN 100387066977
    LC Control Number74002550

    Breast cancer affects one in eight women during their lives. No one knows why some women get breast cancer, but there are many risk factors. Risks that you cannot change include. Genes - two genes, BRCA1 and BRCA2, greatly increase the risk. Women who have family members with breast or ovarian cancer may wish to be tested for the genes.


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The etiology of human breast cancer by Anaxagoras N. Papaioannou Download PDF EPUB FB2

Camile C. Fontelles, Thomas P. Ong, in Advances in Cancer Research, Long-Term Influence of Early-Life Se Exposure on Later Breast Cancer Risk. The fetal period is of particular importance to the etiology of breast cancer, given that it is one of the developmental periods (together with puberty and pregnancy) in which the mammary gland is undergoing extensive.

Since the s, knowledge of the precise molecular etiology of cancer has led to the identification of many cancer-specific abnormalities and the development of targeted treatments tailored to reverse these changes.

The most obvious examples are in breast and prostate cancer, for which the nuclear hormone receptor— the estrogen receptor in. The Etiology of Human Breast Cancer Endocrine, Genetic, Viral, Immunologic and Other Considerations.

Authors About this book. Much of what underlies the current controversy stems from our ignorance concerning the etiology of breast cancer and our inability to comprehend the many eccentricities of its clinical behavior.

The Etiology of Human Breast Cancer Endocrine, Genetic, Viral, Immunologic and Other Considerations. Authors: Papaioannou, A.N. Free Preview. Buy this book eB08 € price for Spain (gross) Buy eBook ISBN ; Digitally watermarked, DRM-free About this book.

Breast cancer, the most frequently occurring cancer in women, is a major public health problem, with 1, estimated new cases worldwide with nearlyrelated deaths.

Breast cancer is highly heterogeneous in its pathological characteristics, some cases showing slow growth with excellent prognosis, while others being aggressive tumors. Current Cited by: The Etiology of Human Breast Cancer: Endocrine, Genetic, Viral, Immunologic and Other Considerations: Medicine & Health Science Books @ ed by: 1.

Good Evening Everybody. I’m Dr. Abhilash from Dept of Radiotherapy. My topic for today is Etiology of Cancer. US cancer researchers Douglas Hanahan and Robert Weinberg Prof Weinberg also discovered the first human oncogene Ras and the first tumor supressor gene Rb.; Estimated million cancer cases around the world in (GLOBOCAN) and.

The four areas that he has covered in greatest extent are endocrine, genetic, viral, and immunologic considerations The etiology of human breast cancer book the etiology of breast cancer.

Within each of these areas, he has been very broad in providing background information, new concepts, and a Cited by: 1.

The etiology of human breast cancer; endocrine, genetic, viral, immunologic and other considerations. The NCI Dictionary of Cancer Terms features 8, terms related to cancer and medicine.

We offer a widget that you can add to your website to let users look up cancer-related terms. Get NCI’s Dictionary of Cancer Terms Widget. EPIDEMIOLOGY. Breast cancer is the most common cancer of adult females all over the world, 7 and after lung cancer, it is the second leading cause of cancer death.

1 As a result of its common occurrence in the Western countries, 1 in 12 women in England and Wales will develop the disease in their lifetime.

2 But this risk is believed by some other workers to be higher and. Etiology of Breast and Gynecological Cancers explores a wide variety of topics, including: * recent advances in the molecular genetics of hereditary breast and ovarian cancer * molecular perspectives on cancer, the cell cycle, and the inherited disorder ataxia-telangiectasia * genotoxicity of environmental agents in human mammary epithelial cells.

@article{osti_, title = {Epidemiology and etiology of ovarian cancer: a review}, author = {Heintz, A.P. and Hacker, N.F. and Lagasse, L.D.}, abstractNote = {Ovarian cancer is the most frequent cause of death from gynecologic malignancies in the western world.

Much effort has been put into attempts to correlate differences in incidence rates with environmental. Breast cancer is a complex, heterogeneous, and multifactorial disease.

Although some genetic factors a strong and wellhave -defined impact, such as mutations in the breast cancer 1(BRCA1) and BRCA2 genes, most of the women who develop the disease do not present a clearly identifiable risk profile [12]. Only 5–10% of all,File Size: KB. Breast Cancer Pathophysiology Breast cancer is a malignant tumor that starts in the cells of the breast.

Like other cancers, there are several factors that can raise the risk of getting breast cancer. subsequently as a paperback book. These authors summarized the scientific literature in order to estimate the proportions of cancer deaths due to avoidable causes in the U.S., based on a complex series of arguments and interpretations of the epidemiologic data.

They produced a summary table that estimated. Limiting carcinogenic exposures in the environment and in the workplace provides an opportunity to reduce the cancer burden, particularly for workers with unacceptably high exposures. Outdoor air pollution causes between 6 and 8 million premature deaths from lung cancer and other diseases each year.

A reanalysis of women with breast cancer and controls from 54 epidemiological studies reported a relative risk of (95%CI: ) among current users, and a relative risk of (95%CI: ) among previous users who discontinued usage for 5.

Variables Related to Human Breast Cancer was first published in The question of what role, if any, heredity plays in the etiology of human cancer is of obvious importance in the continuing search for an answer to the riddle of by:   Breast cancer is the most common invasive cancer in women and the second leading cause of cancer death in women after lung cancer.

Advances in screening and treatment for breast cancer have. It is the only animal breast cancer with a known etiology. These findings are taken to mean that a viral origin of human breast cancer is at least possible, though there is no definitive evidence to support the claim that MMTV causes human breast cancer.

For example, there may be critical differences between cancer pathogenesis in mice and people. Cancer is a disease caused by genetic changes leading to uncontrolled cell growth and tumor formation. The basic cause of sporadic (non-familial) cancers is DNA damage [citation needed] and genomic instability.

A minority of cancers are due to inherited genetic mutations. Most cancers are related to environmental, lifestyle, or behavioral exposures. Cancer is generally. Book Description: Variables Related to Human Breast Cancer was first published in The question of what role, if any, heredity plays in the etiology of human cancer is of obvious importance in the continuing search for an answer to the riddle of cancer.

The Genetic Basis of Cancer. J aime F. M odiano. This is an exciting and rapidly evolving time in the field of cancer genetics. Although it has been clear for several decades that cancer is a disease driven by the accumulation of genetic abnormalities, 1,2 new technologies are rapidly unraveling nuances in how heritable traits influence epigenetics and the tumor environment.

Cancer etiology research investigates biological agents and host predisposing states that are possible etiological factors or cofactors in cancer.

Biological agents are primarily viruses and bacteria but also include endogenous retroviruses, protozoans, fungi, and other multicellular pathogens involved in the initiation, promotion, or.

Introduction. Breast cancer is a heterogeneous disease at the morphological, molecular and genomic level, defining subtypes with distinct biological and clinical behavior. Expression of hormone receptors (HR; i.e., estrogen receptor (ER) or progesterone receptor (PR)) distinguishes two classes of tumors thought to derive from different cells of origin: HR+ tumors deriving from Cited by: 4.

Data on known risk factors for human breast cancer are reviewed. The major predictors of risk are age, geographic area of residence, age at first birth, certain indicators of ovarian activity, history of benign breast disease, and familial history of breast cancer.

Specific aetiological hypotheses are also reviewed, with consideration of the extent to which they explain, or are consistent with, Cited by: Cancer is a myriad collection of diseases with as many different manifestations as there are tissues and cell types in the human body, involving innumerable endogenous or.

breast lumps can increase a woman's risk of getting breast cancer. Any breast lump or change needs to be checked by a health care professional to determine if it is benign or malignant (cancer) and if it might affect your future cancer risk.

See. Breast cancer and Hormonal contraceptives: collaborative reanalysis of individual data on 53, women with breast cancer andwomen without breast cancer from 54.

Get this from a library. The Etiology of Human Breast Cancer: Endocrine, Genetic, Viral, Immunologic and Other Considerations. [Anaxagoras N Papaioannou] -- Breast cancer is probably the most frequent and fatal neoplasm in women of the western world, and it causes more fear, suffering and morbidity than any other disease in our times.

It is also one of. Cancer incidence • World wide cancer related death – 20 % • In US- cancer is second most common cause of death • Most common cancer in developed countries are lung, breast, prostate and colorectal • Most common cancer in developing countries are liver, cervical and oesophageal.

Summary This chapter contains sections titled: Leukemias and Lymphomas Epidemiological Data The Target Cell Conditioning Model References Human Breast Cancer Other Human Cancers Possibly Linked to.

This symposium has been planned to explore the role of endogenous estrogens in the etiology of human breast and prostate cancer. An international group of scientists will share viewpoints and construct a more holistic understanding of the way estrogens induce cancer. Although the etiology of breast cancer is unknown, numerous risk factors may influence the development of this disease including genetic, hormonal, environmental, sociobiological and physiological factors.

Over the past few decades, while the risk of developing breast cancer has increased in both industrialized and developing countriesFile Size: KB. Buy The Etiology of Human Breast Cancer by A.

Papaioannou from Waterstones today. Click and Collect from your local Waterstones or get FREE UK delivery on orders over £Pages: Breast cancer is the most prevalent cancer type among women.

Despite recent progress in early detection and therapeutic strategies, the rate of mortality is increasing. Anti-estrogens or aromatase inhibitors are preferred to treat the women diagnosed with estrogen-receptor (ER) positive tumors.

However, breast tumors usually show intra-tumoral heterogeneity with ER Cited by: 1. When your breast was biopsied, the samples taken were studied under the microscope by a specialized doctor with many years of training called a pathologist.

The pathologist sends your doctor a report that gives a diagnosis for each sample taken. Information in this report will be used to help manage your care.

Breast Cancer and the Environment reviews the current evidence on a selection of environmental risk factors for breast cancer, considers gene-environment interactions in breast cancer, and explores evidence-based actions that might reduce the risk of breast cancer.

The book also recommends further integrative research into the elements of the. @article{osti_, title = {The role of chemicals and radiation in the etiology of cancer}, author = {Huberman, E.

and Barr, S.H.}, abstractNote = {In this volume, investigators consider the mechanisms of oncogenesis, cell transformation, and carcinogen metabolism and present new findings on chemical and radiation carcinogenesis and chemically induced mutagenesis and.

The invasive breast carcinomas consist of several histologic subtypes; the estimated percentages are from a contemporary population-based series ofwomen with breast cancer reported to the Surveillance, Epidemiology, and End Results (SEER) database of the National Cancer Institute between and The authors, in their Fungalbionic Series, detail the fungi/mycotoxin etiology of the above-named human diseases.

In their recent book, Prevention of Breast Cancer: Hope At Last, they identify the fungi/ mycotoxins that contaminate our foods and produce breast cancer.

Thus, having outlined for us which meats, grains, vegetables, fruits, legumes. Introduction. Breast cancer is the most common cancer diagnosed in women in the United States with overcases per year ().Survivors of breast cancer are at increased risk of a second cancer, frequently thyroid cancer ().Thyroid cancer, which also predominantly affects women, is of great concern as the incidence in the United States has more than tripled over Cited by: 4.